KCNJ14

KCNJ14
Identifiers
Aliases	KCNJ14, IRK4, KIR2.4, potassium voltage-gated channel subfamily J member 14, potassium inwardly rectifying channel subfamily J member 14
External IDs	OMIM: 603953; MGI: 2384820; HomoloGene: 27086; GeneCards: KCNJ14; OMA:KCNJ14 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	48,466,980 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	45,474,206 bp
RNA expression pattern
	Top expressed in
	putamen; ; stromal cell of endometrium; ; gastrocnemius muscle; ; skin of abdomen; ; caudate nucleus; ; skeletal muscle tissue; ; prefrontal cortex; ; bone marrow; ; ganglionic eminence; ; cerebellum;
	Top expressed in
	anterior horn of spinal cord; ; eyelid; ; olfactory cortex; ; spinal ganglia; ; lower eyelid; ; amygdala; ; upper eyelid; ; trigeminal ganglion; ; septum of telencephalon; ; autonomic nervous system;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	voltage-gated ion channel activity; inward rectifier potassium channel activity;
Cellular component	integral component of membrane; voltage-gated potassium channel complex; neuronal cell body; plasma membrane; dendrite; membrane;
Biological process	potassium ion transport; regulation of ion transmembrane transport; ion transport; potassium ion import across plasma membrane; cardiac conduction;
	Sources:Amigo / QuickGO
Orthologs
	3770
	211480
	ENSG00000182324
	ENSMUSG00000058743
	Q9UNX9
	Q8JZN3
	NM_170720; NM_013348
	NM_145963
	NP_037480
	NP_666075
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium inwardly-rectifying channel, subfamily J, member 14 (KCNJ14), also known as K_ir2.4, is a human gene.^[5]

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel, and probably has a role in controlling the excitability of motor neurons. Two transcript variants encoding the same protein have been found for this gene.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000182324 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000058743 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: KCNJ14 potassium inwardly-rectifying channel, subfamily J, member 14".

External links

KCNJ14+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This membrane protein–related article is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000182324 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000058743 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: KCNJ14 potassium inwardly-rectifying channel, subfamily J, member 14".

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KCNJ14

See also

References

Further reading

External links