HCN3

HCN3
Identifiers
Aliases	HCN3, hyperpolarization activated cyclic nucleotide gated potassium channel 3
External IDs	OMIM: 609973; MGI: 1298211; HomoloGene: 22453; GeneCards: HCN3; OMA:HCN3 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	155,289,848 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	89,067,503 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; testicle; ; ganglionic eminence; ; mucosa of transverse colon; ; ventricular zone; ; pituitary gland; ; anterior pituitary; ; hypothalamus; ; superior frontal gyrus; ; right frontal lobe;
	Top expressed in
	entorhinal cortex; ; pineal gland; ; barrel cortex; ; spinal ganglia; ; olfactory bulb; ; neural tube; ; medulla oblongata; ; mesencephalon; ; primary motor cortex; ; ventromedial nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; potassium channel activity; cAMP binding; sodium channel activity; voltage-gated ion channel activity; ion channel activity; voltage-gated potassium channel activity; voltage-gated sodium channel activity; protein binding;
Cellular component	integral component of membrane; membrane; plasma membrane; synapse; neuronal cell body; axon; dendrite; cone cell pedicle; integral component of plasma membrane;
Biological process	sodium ion transmembrane transport; sodium ion transport; cellular response to dopamine; regulation of membrane potential; regulation of ion transmembrane transport; ion transport; potassium ion transport; response to cisplatin; transmembrane transport; potassium ion transmembrane transport; cellular response to cAMP;
	Sources:Amigo / QuickGO
Orthologs
	57657
	15168
	ENSG00000143630; ENSG00000263324
	ENSMUSG00000028051
	Q9P1Z3
	O88705
	NM_020897
	NM_008227
	NP_065948
	NP_032253
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 is a protein that in humans is encoded by the HCN3 gene.^[5]^[6]

References

^ ^a ^b ^c ENSG00000263324 GRCh38: Ensembl release 89: ENSG00000143630, ENSG00000263324 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028051 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Hofmann F, Biel M, Kaupp UB (Dec 2005). "International Union of Pharmacology. LI. Nomenclature and structure-function relationships of cyclic nucleotide-regulated channels". Pharmacol Rev. 57 (4): 455–62. doi:10.1124/pr.57.4.8. PMID 16382102. S2CID 45853869.
^ "Entrez Gene: HCN3 hyperpolarization activated cyclic nucleotide-gated potassium channel 3".

External links

HCN3+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This membrane protein–related article is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] ENSG00000263324 GRCh38: Ensembl release 89: ENSG00000143630, ENSG00000263324 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000028051 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid16382102-5] Hofmann F, Biel M, Kaupp UB (Dec 2005). "International Union of Pharmacology. LI. Nomenclature and structure-function relationships of cyclic nucleotide-regulated channels". Pharmacol Rev. 57 (4): 455–62. doi:10.1124/pr.57.4.8. PMID 16382102. S2CID 45853869.

[entrez-6] "Entrez Gene: HCN3 hyperpolarization activated cyclic nucleotide-gated potassium channel 3".

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HCN3

See also

References

Further reading

External links